Associate Scientist- Process Dev. Downstream and Formulation

GENERAL DESCRIPTION:

Precigen is a dedicated commercial, discovery and clinical stage biopharmaceutical company advancing the next generation of gene and cell therapies using precision technology to target the most urgent and intractable diseases in our core therapeutic areas of immuno-oncology, autoimmune disorders, and infectious diseases.

Precigen has developed novel manufacturing processes to deliver UltraCAR-T and AdenoVerse immunotherapies to patients. We have multiple products being evaluated in the clinic using our innovative manufacturing approach to cell and gene therapies.

Associate Scientist - Process Development Downstream and Formulation requires a professional who thrives in a dynamic team environment, brings meticulous attention to detail in the quality of their work and is proactive in implementing improvements. This position will be supporting all CMC aspects of late stage to commercialization of adenovector products.

DUTIES AND RESPONSIBILITIES:

• Perform hands on work in the process development labs to execute experiments with downstream vector purification systems such as ultracentrifuges, chromatography systems, and tangential flow filtration (TFF).

• Assist in formulation development activities including excipient screening, stability studies and commercial in-use conditions of adenovector products.
• Hands on experience in analytical assays like HPLC, DLS, ELISA, SDS-PAGE.
• Document study results in notebooks, forms, and technical reports.
• Communicate and present scientific findings in process development groups.

EDUCATION AND EXPERIENCE:

• BS or MS in Chemical Engineering, Biotechnology or another relevant engineering / scientific qualification. Level will be determined based on education and experience.
• Minimum three (3)+ years of hands-on laboratory experience in Downstream purification or Drug product development
• Strong computer skills with Microsoft Office and the ability to quickly learn new applications.
• Experience in Summarizing and presenting data and authoring technical reports.

DESIRED KEY COMPETENCIES:

• Critical thinking and strong quantitative and analytical skills.
• Self-organizer, meticulous hands-on habits, keen attention to detail.
• Perform other responsibilities to support the needs of the department, as assigned.
• Excellent interpersonal, verbal and written communication skills are essential in this collaborative work environment.
• Ability to understand and execute the company's mission and values.
• Maintain a high degree of ethical standard and trustworthiness.
• Exhibits and open mindset when approaching challenges and conflict.
• Ability to think and adapt to a rapidly changing environment and demands.

Working conditions and physical requirements:

• Must be able to lift, carry, push and/or pull 40 pounds of equipment or supplies.
• May need to work with hazardous materials.
• Able to stand up to 4 hours at a time.